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Hydrochlorothiazide passes into breast milkIt is unknown if amiloride passes into breast milkDiscuss the risks and benefits with your doctor before breast-feeding.

Drug/laboratory testsBecause thiazides may affect calcium metabolismModureticmay interfere with tests for parathyroid function.

Hypokalaemia may developespecially as a result of brisk diuresisafter prolonged therapy or when severe cirrhosis is presentHypokalaemia can sensitise or exaggerate the response of the heart to the toxic effects of digitalise.gincreased ventricular irritability

‘Modureticis intended for the treatment of patients in whom potassium depletion might be suspected or anticipatedThe presence of amiloride hydrochloride minimises the likelihood Cheap lozol medication of potassium loss during vigorous diuresis for long-term maintenance therapyThe combination is thus indicated especially in conditions where potassium balance is particularly important.

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